Change in Scope

Click here to access the Change in Scope section of the Post-Award Sponsored Projects Guide on page 32.

Change in Scope of Work

Any proposed change in the specific aims of the project as stated in the proposal or approved modifications, and/or any proposed change in the protocol, requires approval from the awarding agency. Examples of changes that require sponsor approval include, but are not limited to:

  • Substitution of one animal mode for another
  • Any change from the approved use of animals or human subjects
  • Shifting the emphasis of the research from one disease area to another.


When in doubt, it is best to err on the side of over-communicating with the program office.